Tribune News Service
New Delhi, April 19
India’s apex medical research body ICMR on Monday shared data from hospitalized COVID patients during the first and the second wave of the pandemic, saying that there is no evidence of the younger population being at greater risk in the ongoing wave and that the proportion of death in the hospitalized patients also has not changed between the two spells.
What has changed is more hospitalized patients (47.5 pc) reporting shortness of breath in the second wave than in the first (41.7 pc), significantly raising the requirement of supplemental oxygen in the country in the ongoing wave.
Also more asymptomatic people have been admitted to hospitals in the second wave, of which the ICMR has done interim analysis and larger studies are ongoing.
More than 70 per cent of the hospitalized COVID patients in both waves have been over 40 years old, data from 9,485 patients (6,642 between September and November 2020 and 1,405 between March and April 2021) shows.
Only marginally higher number of youth (0 to 18 years) have been hospitalized this time – 5.8 per cent as against 4.2 per cent last year despite the opening up of economic activities, the ICMR study says.
Even the Integrated Disease Surveillance Programme data, which the Member Health NITI Aayog today shared, shows 31 per cent of the 49,000 COVID infected last year were under 30 years as against 32 per cent among 50,000 positive persons this time.
“The proportion of 30- to 40-year-olds has remained static at 21 per cent between the two waves.” The conclusion is that there is no overarching extra risk to the youth of becoming COVID positive this time. There has been no shift in the age prevalence of COVID in India. The older people continue to be more vulnerable, ”Paul said today.
The government experts also came out to caution people against irrational use of remdesivir noting that no study in the world had shown it reduced mortality.
“Remdesivir is only to be used in moderately ill COVID patients who are hospitalized, and have very low oxygen levels and lung damage. It is of no use in mild patients. In fact, UK has only given paracetamol, hydration and multi-vitamins to mild patients and that’s the way management, ”AIIMS-New Delhi Director Randeep Guleria said, noting that Remdesivir was no magic bullet and this anti-viral injection was not meant to be taken at home.
On plasma therapy, the AIIMS Director said large studies in India had shown it was not useful in COVID patients.
On Tocilizumab, he said it meant for severely ill COVID patients in whom cytokine storm had set in and no other treatment — steroids, anti-coagulants, etc. – was working.
Paul also said people must understand Remdesivir was not a mainstay drug for COVID and was used in hospitalized patients only because no other effective anti viral was available.
“Remdesivir is an experimental drug cleared for emergency use. It is not to be taken in home settings, ”said Paul.
The experts’ message to people with mild illness was not to panic and to follow basic home management.
ICMR Chief Balram Bhargava said oxygen remained critical to COVID management and its use has increased because several people got treated to hospitals out of panic.
Medical oxygen availability was being ramped up across India, said Paul.
All about Covid drugs
Mild patients will recover at home with paracetamol, hydration, multi vitamins
Remdesivir: No magic bullet; useful only in hospitalized patients with low oxygen; does not reduce deaths; of no use in mild patients
Steroids: Useful in moderate to severely
I’ll, but must be given at the right time, mortality is higher if given before oxygen levels fall too low
Plasma: No evidence that it’s useful
Tocilizumab: Needed in less than 2 pc Covid patients who are severely ill and in whom steroids and other drugs have stopped working